Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318574 | 0.87 | MEN1 (0.41) | SIRT3MEN1KMT2ADRD2SMN1; SMN2 | |
| SCHEMBL7310172 | 0.85 | DRD2 (0.41) | SIRT3MEN1KMT2ADRD2SMN1; SMN2 | |
| SCHEMBL7312987 | 0.80 | L3MBTL1 (0.41) | SIRT3MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7308539 | 0.80 | SIRT3 (0.52) | SIRT3MEN1KMT2ADRD2SMN1; SMN2 | |
| SCHEMBL7320383 | 0.74 | SMN1; SMN2 (0.47) | SIRT3MEN1KMT2ADRD2SMN1; SMN2 | |
| SCHEMBL7311801 | 0.73 | SMN1; SMN2 (0.41) | SIRT3MEN1KMT2ADRD2SMN1; SMN2 | |
| SCHEMBL7317245 | 0.69 | PDE3B (0.44) | MEN1KMT2AL3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL7315213 | 0.68 | L3MBTL1 (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1CYP2D6 | |
| SCHEMBL7308462 | 0.68 | PDE3B (0.36) | MEN1KMT2ADRD2SMN1; SMN2CNR1 | |
| SCHEMBL7318581 | 0.68 | L3MBTL1 (0.41) | SMN1; SMN2L3MBTL1CYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |