Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.43 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.43 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.43 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.43 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.43 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.43 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309944 | 0.88 | MMEL1 (0.61) | MMEL1L3MBTL1ADCY6ADCY3ADCY9 | |
| SCHEMBL7319489 | 0.83 | CTSS (0.49) | CTSSCTSKMMEL1L3MBTL1CTSB | |
| SCHEMBL7308481 | 0.83 | CTSS (0.49) | CTSSCTSKMMEL1L3MBTL1CTSB | |
| SCHEMBL7312131 | 0.80 | MEN1 (0.44) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7308501 | 0.79 | MMEL1 (0.43) | CTSSCTSKMMEL1ADCY6ADCY3 | |
| SCHEMBL1912530 | 0.79 | MMEL1 (0.61) | CTSSCTSKMMEL1ADCY6ADCY3 | |
| SCHEMBL2873780 | 0.79 | MMEL1 (0.61) | CTSSCTSKMMEL1ADCY6ADCY3 | |
| SCHEMBL7322706 | 0.78 | MME (0.59) | — | |
| SCHEMBL7348036 | 0.78 | MME (0.59) | — | |
| SCHEMBL7318671 | 0.77 | HDAC1 (0.52) | CTSSCTSKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |