Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312123 | 0.85 | MEN1 (0.43) | MEN1ALDH1A1HPGDKMT2AITGB3 | |
| SCHEMBL7312143 | 0.82 | FOLH1 (0.42) | MEN1ALDH1A1HPGDKMT2AMMP2 | |
| SCHEMBL7308495 | 0.80 | CTSS (0.52) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7319346 | 0.79 | MEN1 (0.40) | MEN1ALDH1A1HPGDKMT2ATERT | |
| SCHEMBL7309944 | 0.78 | MMEL1 (0.61) | MME | |
| SCHEMBL7316905 | 0.75 | L3MBTL1 (0.45) | MEN1ALDH1A1HPGDKMT2AMME | |
| SCHEMBL7322563 | 0.74 | HRH4 (0.50) | MEN1ALDH1A1HPGDKMT2AHRH4 | |
| SCHEMBL7322667 | 0.74 | HRH4 (0.50) | MEN1ALDH1A1HPGDKMT2AHRH4 | |
| SCHEMBL14598315 | 0.73 | CTSS (0.64) | MEN1ALDH1A1HPGDKMT2ACTSL | |
| Bromide SCHEMBL7311466 | 0.72 | MME (0.45) | ITGB3ITGA2BMMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |