Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316727 | 0.86 | PDE3B (0.40) | PDE3BPDE3AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7320214 | 0.85 | PDE3B (0.39) | PDE3BPDE3AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10376732 | 0.85 | PDE3B (0.44) | PDE3BPDE3AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7310244 | 0.82 | L3MBTL1 (0.39) | PDE3BPDE3AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10375858 | 0.81 | ALDH1A1 (0.39) | PDE3BPDE3AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7309568 | 0.81 | PDE3B (0.47) | PDE3BPDE3AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7311187 | 0.81 | MCL1 (0.43) | PDE3BPDE3AMAPTTHRATHRB | |
| Hydrochloric Acid SCHEMBL7305466 | 0.80 | MCL1 (0.42) | PDE3BPDE3AMAPTTHRATHRB | |
| SCHEMBL10375666 | 0.80 | PDE3B (0.47) | PDE3BPDE3AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7319384 | 0.78 | MAPT (0.40) | ALDH1A1MAPTL3MBTL1KMT2ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |