Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316727 | 0.86 | PDE3B (0.40) | PDE3BPDE3AALDH1A1THRATHRB | |
| SCHEMBL7308733 | 0.85 | PDE3B (0.39) | PDE3BPDE3AALDH1A1THRATHRB | |
| SCHEMBL7318978 | 0.82 | PPARG (0.39) | PDE3BPDE3AALDH1A1KDM4ELMNA | |
| SCHEMBL7315992 | 0.81 | PDE3B (0.49) | PDE3BPDE3AALDH1A1KDM4ELMNA | |
| SCHEMBL10376732 | 0.74 | PDE3B (0.44) | PDE3BPDE3AALDH1A1KDM4ELMNA | |
| SCHEMBL7319242 | 0.74 | LMNA (0.40) | PDE3BPDE3AALDH1A1KDM4ELMNA | |
| SCHEMBL7310244 | 0.73 | L3MBTL1 (0.39) | PDE3BPDE3AALDH1A1THRATHRB | |
| SCHEMBL7317629 | 0.73 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL7314934 | 0.72 | ALDH1A1 (0.41) | ALDH1A1THRATHRBKDM4ELMNA | |
| SCHEMBL10375858 | 0.72 | ALDH1A1 (0.39) | PDE3BPDE3AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |