Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308733 | 0.86 | PDE3B (0.39) | PDE3BPDE3AALDH1A1L3MBTL1MAPT | |
| SCHEMBL7320214 | 0.86 | PDE3B (0.39) | PDE3BPDE3AALDH1A1L3MBTL1MAPT | |
| SCHEMBL7319242 | 0.82 | LMNA (0.40) | PDE3BPDE3AALDH1A1L3MBTL1MAPT | |
| SCHEMBL7318784 | 0.81 | PDE3B (0.47) | PDE3BPDE3AALDH1A1MAOBL3MBTL1 | |
| SCHEMBL10376732 | 0.75 | PDE3B (0.44) | PDE3BPDE3AALDH1A1L3MBTL1MAPT | |
| SCHEMBL7310244 | 0.74 | L3MBTL1 (0.39) | PDE3BPDE3AALDH1A1L3MBTL1MAPT | |
| SCHEMBL7318978 | 0.74 | PPARG (0.39) | PDE3BPDE3AALDH1A1L3MBTL1MAPT | |
| SCHEMBL10375858 | 0.72 | ALDH1A1 (0.39) | PDE3BPDE3AALDH1A1L3MBTL1MAPT | |
| SCHEMBL7312404 | 0.72 | ALDH1A1 (0.49) | ALDH1A1MAOBL3MBTL1MAPTLMNA | |
| SCHEMBL10375666 | 0.71 | PDE3B (0.47) | PDE3BPDE3AALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |