Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305243 | 1.00 | ANPEP (0.52) | ANPEPSMN1; SMN2MEN1KMT2AKCNQ2 | |
| SCHEMBL7305558 | 0.82 | KDM4E (0.57) | ANPEPMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7310744 | 0.81 | HPGD (0.49) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL799896 | 0.79 | SMN1; SMN2 (0.70) | ANPEPSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL7310030 | 0.78 | MAPT (0.56) | SMN1; SMN2KMT2ANPC1RAB9AFOLH1 | |
| SCHEMBL7309151 | 0.77 | HTT (0.53) | SMN1; SMN2MEN1KMT2AGRM5KDM4E | |
| SCHEMBL19388858 | 0.77 | SMN1; SMN2 (0.56) | ANPEPSMN1; SMN2MEN1KMT2AKCNQ2 | |
| SCHEMBL27448738 | 0.77 | KCNQ2 (0.54) | SMN1; SMN2MEN1KMT2AKCNQ2NPC1 | |
| SCHEMBL13299580 | 0.77 | SMN1; SMN2 (0.56) | ANPEPSMN1; SMN2MEN1KMT2AKCNQ2 | |
| SCHEMBL7299800 | 0.76 | HPGD (0.67) | SMN1; SMN2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555537-B1 | Endothelin antagonists | BANYU PHARMA CO LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |