Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309632 | 1.00 | MGLL (0.35) | MGLLSSTR4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7301141 | 0.77 | HTR3A (0.54) | SMN1; SMN2 | |
| SCHEMBL7301145 | 0.77 | HTR3A (0.54) | SMN1; SMN2 | |
| SCHEMBL9589583 | 0.76 | CHRNA7 (0.50) | ALDH1A1 | |
| SCHEMBL7306336 | 0.76 | CHRNA7 (0.50) | ALDH1A1 | |
| SCHEMBL7306346 | 0.76 | CHRNA7 (0.50) | ALDH1A1 | |
| SCHEMBL7309504 | 0.72 | RAB9A (0.56) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| SCHEMBL7304782 | 0.69 | KDM4E (0.50) | SSTR4KDM4EALDH1A1HSD17B10TLR8 | |
| SCHEMBL361263 | 0.69 | MEN1 (0.51) | — | |
| SCHEMBL16795980 | 0.69 | MEN1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483836-A1 | Pyrazolo [1,5-a] pyridine-3-carboxylic acid derivatives, their preparation process and their use | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-05-06 | — | — | EP | disclosed |