Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314509 | 0.98 | SIGMAR1 (0.34) | SIGMAR1DRD2HRH2HRH1CHRM2 | |
| SCHEMBL7301524 | 0.97 | SIGMAR1 (0.34) | SIGMAR1DRD2HRH2HRH1CHRM2 | |
| SCHEMBL7314629 | 0.97 | SIGMAR1 (0.34) | SIGMAR1DRD2HRH2HRH1CHRM2 | |
| SCHEMBL7315701 | 0.95 | SIGMAR1 (0.34) | SIGMAR1DRD2HRH2HRH1CHRM2 | |
| SCHEMBL7307310 | 0.94 | GPR119 (0.32) | SIGMAR1DRD2CHRM2CHRM1 | |
| SCHEMBL7309062 | 0.93 | ITGB3 (0.34) | SIGMAR1DRD2HRH2HRH1CHRM2 | |
| SCHEMBL7316594 | 0.93 | DRD2 (0.33) | SIGMAR1DRD2CHRM2CHRM1 | |
| SCHEMBL7314220 | 0.92 | SIGMAR1 (0.36) | SIGMAR1DRD2HRH2HRH1CHRM2 | |
| SCHEMBL7316078 | 0.92 | DRD2 (0.33) | SIGMAR1DRD2CHRM2CHRM1 | |
| SCHEMBL7305537 | 0.92 | ITGB3 (0.34) | SIGMAR1DRD2HRH2HRH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |