Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13436116 | 0.82 | MEN1 (0.53) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL7309838 | 0.80 | SCN4A (0.47) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL7302727 | 0.80 | SCN4A (0.53) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL9288424 | 0.77 | LMNA (0.51) | SCN4ACTSCMEN1KMT2AGHSR | |
| SCHEMBL27394991 | 0.77 | SCN4A (0.48) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL2092282 | 0.76 | SCN4A (0.47) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL2092281 | 0.76 | SCN4A (0.47) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL9279932 | 0.75 | MEN1 (0.52) | SCN4ACTSCMEN1KMT2AGHSR | |
| SCHEMBL13964105 | 0.75 | CTSC (0.51) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL18555397 | 0.75 | SCN4A (0.45) | SCN4ACTSCHTR2CHTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064559-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |