Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305673 | 0.94 | HRH3 (0.31) | SMN1; SMN2HRH3DRD2DRD3HTR2A | |
| SCHEMBL7314775 | 0.92 | HRH3 (0.36) | ALDH1A1HRH3 | |
| SCHEMBL7313111 | 0.89 | HRH3 (0.31) | HRH3DRD2DRD3 | |
| SCHEMBL7306138 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4EALDH1A1TP53 | |
| SCHEMBL7309115 | 0.86 | HTR7 (0.38) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7309143 | 0.86 | CYP1A2 (0.32) | SMN1; SMN2HRH3DRD2DRD3 | |
| SCHEMBL7315517 | 0.85 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EALDH1A1TP53DRD2 | |
| SCHEMBL7304254 | 0.84 | HRH3 (0.33) | HRH3 | |
| SCHEMBL8659057 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EALDH1A1HRH3TP53 | |
| SCHEMBL7303836 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EALDH1A1HRH3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |