Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313310 | 0.96 | MAOB (0.35) | SMN1; SMN2MAOBDAOFPR3FPR2 | |
| SCHEMBL7311515 | 0.89 | MAOB (0.37) | SMN1; SMN2MAOBDAOHTR4 | |
| SCHEMBL7314712 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EALDH1A1FPR3FPR2 | |
| SCHEMBL7309953 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4EALDH1A1TP53 | |
| SCHEMBL7314586 | 0.87 | MAOB (0.37) | SMN1; SMN2MAOBDAOKDM1AHTR4 | |
| SCHEMBL7313049 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EALDH1A1FPR3FPR2 | |
| SCHEMBL7305673 | 0.86 | HRH3 (0.31) | SMN1; SMN2HTR4KEAP1NFE2L2SIGMAR1 | |
| SCHEMBL7300811 | 0.85 | MAOB (0.37) | MAOBDAOHTR4SIGMAR1 | |
| SCHEMBL7317073 | 0.85 | MEN1 (0.33) | SMN1; SMN2ALDH1A1FPR3FPR2ACHE | |
| SCHEMBL7306902 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EALDH1A1TP53KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |