Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309953 | 0.94 | SMN1; SMN2 (0.36) | HRH3SMN1; SMN2HTR2ADRD2DRD3 | |
| SCHEMBL7314775 | 0.91 | HRH3 (0.36) | HRH3SIGMAR1 | |
| SCHEMBL7309143 | 0.90 | CYP1A2 (0.32) | HRH3SMN1; SMN2CHRM2ADRA2BHRH1 | |
| SCHEMBL7313310 | 0.90 | MAOB (0.35) | SMN1; SMN2HTR4SIGMAR1KEAP1NFE2L2 | |
| SCHEMBL7309020 | 0.86 | CHRM2 (0.38) | SMN1; SMN2CHRM2 | |
| SCHEMBL7311246 | 0.86 | DRD2 (0.35) | SMN1; SMN2HTR4CHRM2ADRA2BHRH2 | |
| SCHEMBL7313111 | 0.86 | HRH3 (0.31) | HRH3DRD2DRD3 | |
| SCHEMBL7306138 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2HTR4SIGMAR1KEAP1NFE2L2 | |
| SCHEMBL7314564 | 0.85 | SMN1; SMN2 (0.33) | HRH3HDAC1EHMT1HDAC6SMN1; SMN2 | |
| SCHEMBL8654817 | 0.84 | HDAC1 (0.33) | HDAC1EHMT1HDAC6SMN1; SMN2HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |