Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309143 | 0.94 | CYP1A2 (0.32) | HRH3DRD2DRD3 | |
| SCHEMBL7304254 | 0.91 | HRH3 (0.33) | HRH3 | |
| SCHEMBL7309953 | 0.89 | SMN1; SMN2 (0.36) | HRH3DRD2DRD3 | |
| SCHEMBL7311515 | 0.87 | MAOB (0.37) | GLA | |
| SCHEMBL7305673 | 0.86 | HRH3 (0.31) | HRH3DRD2DRD3 | |
| SCHEMBL7314775 | 0.85 | HRH3 (0.36) | HRH3 | |
| SCHEMBL7300978 | 0.85 | HTR7 (0.39) | — | |
| SCHEMBL7301320 | 0.84 | DRD2 (0.33) | DRD2DRD3GLA | |
| SCHEMBL8661783 | 0.83 | GLA (0.31) | HRH3GLA | |
| SCHEMBL7308443 | 0.83 | ACHE (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |