Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.47 |
| ▸ | CNR1 | P21554 | 6/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4294889 | 0.83 | HTR4 (0.61) | CNR2CNR1KDM1APLK1CYP1A2 | |
| SCHEMBL7308948 | 0.79 | HTR4 (0.49) | CNR2CNR1KDM1APLK1CYP1A2 | |
| SCHEMBL7295769 | 0.76 | HTR4 (0.72) | KDM1ACYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL7304670 | 0.76 | KDM1A (0.46) | KDM1AALDH1A1MAPT | |
| SCHEMBL9543051 | 0.75 | CNR2 (0.52) | CNR2CNR1HRH2 | |
| SCHEMBL7301718 | 0.74 | HTR4 (0.62) | CNR2CNR1KDM1APLK1CYP1A2 | |
| SCHEMBL7331887 | 0.72 | HRH2 (0.54) | CNR2CNR1PLK1HRH2 | |
| SCHEMBL9344560 | 0.71 | CNR1 (0.62) | CNR2CNR1PLK1ALDH1A1 | |
| SCHEMBL7778088 | 0.71 | CNR2 (0.70) | CNR2PLK1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9345149 | 0.71 | CNR2 (0.49) | CNR2CNR1PLK1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501322-B1 | 3-Piperidinylmethylcarboxylate substituted indoles | GLAXO GROUP LTD (GB) | 1996-09-04 | — | — | EP | claimed |