Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317102 | 0.91 | ITGB3 (0.42) | ITGB3ITGA2BMAPK1L3MBTL1HTR2B | |
| SCHEMBL7317060 | 0.91 | MAPK1 (0.37) | ITGB3ITGA2BMAPK1L3MBTL1HTR2B | |
| SCHEMBL7314702 | 0.91 | SMN1; SMN2 (0.38) | ITGB3ITGA2BMAPK1L3MBTL1HTR2B | |
| SCHEMBL7313586 | 0.89 | ITGB3 (0.43) | ITGB3ITGA2BMAPK1L3MBTL1HTR2B | |
| SCHEMBL7313570 | 0.88 | MAPK1 (0.39) | ITGB3ITGA2BMAPK1L3MBTL1HTR2B | |
| SCHEMBL7312627 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BMAPK1L3MBTL1HTR2B | |
| SCHEMBL7313685 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BMAPK1L3MBTL1HTR2B | |
| SCHEMBL7314513 | 0.85 | SIGMAR1 (0.42) | ITGB3ITGA2BMAPK1L3MBTL1HTR2B | |
| SCHEMBL7306376 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BHTR2BSIGMAR1ALDH1A1 | |
| SCHEMBL7315390 | 0.84 | HTR7 (0.39) | ITGB3ITGA2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |