Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306892 | 0.92 | SMN1; SMN2 (0.41) | ITGB3ITGA2BHTR2BHRH3SIGMAR1 | |
| SCHEMBL7303812 | 0.90 | MAOA (0.36) | ITGB3ITGA2BHTR2BHRH3SIGMAR1 | |
| SCHEMBL7313185 | 0.89 | ITGB3 (0.40) | ITGB3ITGA2BHTR2BSIGMAR1 | |
| SCHEMBL7308424 | 0.87 | ITGB3 (0.45) | ITGB3ITGA2BHTR2BSIGMAR1SMN1; SMN2 | |
| SCHEMBL7309051 | 0.87 | HTR2B (0.39) | ITGB3ITGA2BHTR2BHRH3SIGMAR1 | |
| SCHEMBL7310445 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BHTR2BSIGMAR1MAPK1 | |
| SCHEMBL7317102 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BHTR2BSIGMAR1MAPK1 | |
| SCHEMBL7305482 | 0.85 | SIGMAR1 (0.44) | ITGB3ITGA2BHTR2BSIGMAR1 | |
| SCHEMBL7305748 | 0.85 | ITGB3 (0.39) | ITGB3ITGA2BHTR2BSIGMAR1MAPK1 | |
| SCHEMBL7316513 | 0.82 | SMN1; SMN2 (0.40) | ITGB3ITGA2BHTR2BSIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |