Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318081 | 0.89 | NFKB1 (0.48) | HTR6NFKB1NFKB2RELA | |
| SCHEMBL7316568 | 0.88 | DRD2 (0.57) | HTR6DRD2DRD1DRD4DRD5 | |
| SCHEMBL7320065 | 0.85 | DRD2 (0.68) | HTR6DRD2DRD1DRD4DRD5 | |
| SCHEMBL7317264 | 0.82 | DRD2 (0.63) | DRD2DRD1DRD4DRD5DRD3 | |
| Oxalic Acid SCHEMBL7311582 | 0.82 | DRD2 (0.72) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL7322386 | 0.81 | HTR6 (0.48) | HTR6DRD2DRD1DRD4DRD5 | |
| SCHEMBL7316933 | 0.81 | DRD2 (0.44) | HTR6DRD2DRD1DRD4DRD5 | |
| SCHEMBL9089665 | 0.80 | HTR6 (0.52) | HTR6DRD2DRD1DRD4DRD5 | |
| SCHEMBL9089984 | 0.77 | DRD2 (0.50) | HTR6DRD2DRD1DRD4DRD5 | |
| SCHEMBL7315074 | 0.77 | HTR6 (0.43) | HTR6DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684039-A | Chroman-2-ylmethylamino derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |