Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315074 | 0.86 | HTR6 (0.43) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7318081 | 0.85 | NFKB1 (0.48) | HTR6 | |
| SCHEMBL7316568 | 0.84 | DRD2 (0.57) | HTR6DRD2DRD4DRD3DRD1 | |
| Oxalic Acid SCHEMBL7320594 | 0.81 | HTR6 (0.68) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7320065 | 0.81 | DRD2 (0.68) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7311588 | 0.81 | HTR6 (0.50) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7321831 | 0.81 | DRD2 (0.66) | DRD2DRD4DRD3DRD1DRD5 | |
| Oxalic Acid SCHEMBL7322376 | 0.81 | DRD2 (0.71) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL9089984 | 0.80 | DRD2 (0.50) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7316933 | 0.79 | DRD2 (0.44) | HTR6DRD2DRD4DRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684039-A | Chroman-2-ylmethylamino derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |