Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207617 | 0.93 | ALDH1A1 (0.58) | KDM4ELMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2209496 | 0.88 | KDM4E (0.62) | KDM4ELMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2204618 | 0.85 | KDM4E (0.52) | KDM4ELMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4155322 | 0.82 | KDM4E (0.58) | KDM4ELMNAALDH1A1HTTRECQL | |
| SCHEMBL7309093 | 0.81 | KDM4E (0.65) | KDM4ELMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7301955 | 0.80 | HTR3A (0.52) | KDM4ELMNA | |
| SCHEMBL7301949 | 0.80 | HTR3A (0.52) | KDM4ELMNA | |
| SCHEMBL2210791 | 0.79 | HTR4 (0.53) | KDM4ELMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1061973 | 0.79 | KDM4E (1.00) | KDM4ELMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8810033 | 0.76 | HTT (0.64) | KDM4ELMNAALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503844-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-5219864-A | Prevention, treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| US-5155115-A | THIENOPYRIDINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0503844-A1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |