Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207617 | 0.90 | ALDH1A1 (0.58) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2204618 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL7312010 | 0.88 | KDM4E (0.65) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL4155322 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1LMNAHTTRECQL | |
| SCHEMBL2210791 | 0.82 | HTR4 (0.53) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2383886 | 0.76 | KDM4E (1.00) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11083105 | 0.73 | KDM4E (0.60) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11068656 | 0.73 | ALDH1A1 (0.76) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL15966835 | 0.72 | ALDH1A1 (1.00) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11486236 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7982040-B2 | Thienopyridinone compounds and methods of treatment | NANOTHERAPEUTICS, INC. (US) | 2011-07-19 | — | — | US | disclosed |
| US-7576211-B2 | Synthesis of thienopyridinone compounds and related intermediates | EPIX DELAWARE, INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-20090163537-A1 | Thienopyridinone Compounds and Methods of Treatment | NANOSHIFT, LLC | 2009-06-25 | — | — | US | disclosed |
| US-7488736-B2 | Thienopyridinone compounds and methods of treatment | EPIX DELAWARE, INC. (US) | 2009-02-10 | — | — | US | disclosed |
| US-20060084805-A1 | Synthesis of thienopyridinone compounds and related intermediates | NANOSHIFT, LLC | 2006-04-20 | — | — | US | disclosed |
| US-20050256153-A1 | Thienopyridinone compounds and methods of treatment | NANOSHIFT, LLC | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163537-A1 | Thienopyridinone Compounds and Methods of Treatment | HTR5A, GIPR, TBXA2R | KDM4E 3279/4885ALDH1A1 762/4885LMNA 1329/4885 |
| US-20060084805-A1 | Synthesis of thienopyridinone compounds and related intermediates | HTR5A, GIPR, HTR1A | KDM4E 3570/4885ALDH1A1 733/4885LMNA 1382/4885 |
| US-20050256153-A1 | Thienopyridinone compounds and methods of treatment | HTR5A, GIPR, TBXA2R | KDM4E 3279/4885ALDH1A1 762/4885LMNA 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.