Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312404 | 0.90 | ALDH1A1 (0.49) | ALDH1A1MAPK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7309568 | 0.85 | PDE3B (0.47) | PDE3BPDE3AALDH1A1MAPK1KMT2A | |
| SCHEMBL7315992 | 0.85 | PDE3B (0.49) | PDE3BPDE3AALDH1A1MAPK1KMT2A | |
| SCHEMBL10375666 | 0.84 | PDE3B (0.47) | PDE3BPDE3AALDH1A1MAPK1KMT2A | |
| SCHEMBL7311180 | 0.83 | PDE3B (0.47) | PDE3BPDE3AALDH1A1MAPK1KMT2A | |
| SCHEMBL7318725 | 0.82 | LMNA (0.54) | PDE3BPDE3AALDH1A1MAPK1KMT2A | |
| SCHEMBL10376732 | 0.82 | PDE3B (0.44) | PDE3BPDE3AALDH1A1MAPK1KMT2A | |
| SCHEMBL7316727 | 0.81 | PDE3B (0.40) | PDE3BPDE3AALDH1A1MAPK1KMT2A | |
| SCHEMBL10377117 | 0.81 | PDE3B (0.42) | PDE3BPDE3AALDH1A1MAPK1KMT2A | |
| SCHEMBL12238285 | 0.76 | MAPT (0.49) | PDE3BPDE3AALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |