Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314481 | 0.91 | FBP1 (0.38) | ALDH1A1VCAM1TDP1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7312508 | 0.89 | FBP1 (0.38) | ALDH1A1VCAM1TDP1PRSS1MAPT | |
| SCHEMBL7307845 | 0.87 | MAPT (0.37) | ALDH1A1MAPK1MAPTKDM4EKMT2A | |
| SCHEMBL7314001 | 0.85 | MAPT (0.41) | ALDH1A1VCAM1TDP1ESR1LMNA | |
| SCHEMBL7315792 | 0.82 | FFAR4 (0.41) | ALDH1A1VCAM1TDP1LMNAMAPT | |
| SCHEMBL7317383 | 0.82 | ALDH1A1 (0.39) | ALDH1A1PRSS1LMNAMAPTKDM4E | |
| SCHEMBL7309665 | 0.81 | LMNA (0.43) | ALDH1A1TDP1LMNAMAPK1KDM4E | |
| SCHEMBL7317613 | 0.80 | PTPN7 (0.32) | ALDH1A1VCAM1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7312485 | 0.80 | NPC1 (0.44) | ALDH1A1PRSS1LMNAMAPK1MAPT | |
| SCHEMBL7310516 | 0.79 | RAB9A (0.37) | ALDH1A1PRSS1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |