Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 17/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 16/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314223 | 0.93 | OPRL1 (0.48) | OPRM1OPRL1OPRK1 | |
| SCHEMBL7750561 | 0.86 | CYP2C19 (0.40) | OPRM1OPRL1OPRK1 | |
| SCHEMBL4631671 | 0.83 | OPRM1 (0.73) | OPRM1OPRL1OPRK1 | |
| SCHEMBL27450087 | 0.83 | OPRM1 (0.49) | OPRM1OPRL1OPRK1 | |
| SCHEMBL7745677 | 0.81 | ALDH1A1 (0.38) | OPRM1OPRL1OPRK1 | |
| SCHEMBL7313869 | 0.81 | OPRM1 (0.56) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL7478467 | 0.81 | OPRM1 (0.69) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL7478459 | 0.81 | OPRM1 (0.69) | OPRM1OPRL1OPRK1 | |
| SCHEMBL4352116 | 0.80 | OPRL1 (0.63) | OPRM1OPRL1OPRK1 | |
| SCHEMBL4298027 | 0.79 | OPRL1 (0.42) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673928-B1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI SYNTHELABO (FR) | 2001-08-29 | — | — | EP | disclosed |
| EP-0673928-A1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI (FR) | 1995-09-27 | — | — | EP | disclosed |