Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314223 | 0.86 | OPRL1 (0.48) | OPRL1OPRM1OPRK1 | |
| SCHEMBL4352116 | 0.82 | OPRL1 (0.63) | OPRL1OPRM1OPRK1 | |
| SCHEMBL7312540 | 0.79 | OPRM1 (0.51) | OPRL1OPRM1OPRK1 | |
| SCHEMBL4004182 | 0.79 | HTT (0.40) | OPRL1OPRM1CHRM3 | |
| SCHEMBL4005230 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL4005563 | 0.76 | LMNA (0.34) | OPRL1OPRM1CHRM3 | |
| SCHEMBL7745677 | 0.75 | ALDH1A1 (0.38) | OPRL1OPRM1OPRK1 | |
| SCHEMBL4007004 | 0.74 | PTGIR (0.34) | OPRL1OPRM1 | |
| SCHEMBL7313593 | 0.73 | CACNA1G (0.53) | OPRL1CHRM3 | |
| SCHEMBL4006087 | 0.71 | SSTR4 (0.54) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |