Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309596 | 0.98 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1MAPTHTR7 | |
| SCHEMBL7314334 | 0.96 | CACNA1G (0.42) | ALDH1A1KMT2AMEN1MAPTHTR7 | |
| SCHEMBL7310167 | 0.94 | CACNA1G (0.42) | ALDH1A1KMT2AMEN1MAPTHTR7 | |
| SCHEMBL7307041 | 0.94 | KMT2A (0.44) | ALDH1A1KMT2AMEN1MAPTHTR7 | |
| SCHEMBL7314518 | 0.94 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL7314139 | 0.93 | CACNA1G (0.42) | ALDH1A1KMT2AMEN1MAPTHTR7 | |
| SCHEMBL7314534 | 0.92 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7311514 | 0.91 | ACHE (0.42) | CHRM4DRD2DRD4 | |
| SCHEMBL7304824 | 0.91 | ACHE (0.43) | CHRM4DRD2DRD4 | |
| SCHEMBL7307606 | 0.91 | CHRM2 (0.43) | ALDH1A1KMT2AHTR7HTR1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |