SCHEMBL7314534

SCHEMBL7314534

COC(=O)CN1CCN(C2OC(=O)N(CCCCN3CCN(Cc4ccccc4)CC3)C2C)CC1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 2/20 0.41
RECQL P46063 1/20 0.41
CCR3 P51677 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7314518 0.98 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TSHRRECQLMEN1
SCHEMBL7305487 0.94 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL7310167 0.94 CACNA1G (0.42) ALDH1A1SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL7309596 0.94 ALDH1A1 (0.43) ALDH1A1TSHRMEN1KMT2A
SCHEMBL7312588 0.92 ALDH1A1 (0.43) ALDH1A1TSHRMEN1KMT2A
SCHEMBL7314334 0.92 CACNA1G (0.42) ALDH1A1SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL7315052 0.91 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2CCR3MEN1KMT2A
SCHEMBL7305852 0.91 ACHE (0.45)
SCHEMBL7317984 0.90 ACHE (0.43)
SCHEMBL7314139 0.90 CACNA1G (0.42) ALDH1A1SMN1; SMN2TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711770-A1 Antagonists of adhesion receptors MERCK PATENT GmbH (DE) 1996-05-15 EP disclosed