Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316959 | 0.86 | ALDH1A1 (0.35) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7312257 | 0.86 | ALDH1A1 (0.37) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7312638 | 0.82 | MAPT (0.35) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7312643 | 0.73 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7321025 | 0.73 | ALDH1A1 (0.39) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL7316945 | 0.71 | ALDH1A1 (0.36) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7312241 | 0.70 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7317001 | 0.70 | MAPT (0.31) | MAPTALDH1A1POLB | |
| SCHEMBL7320610 | 0.69 | PDE3B (0.34) | MAPTALDH1A1POLBCYP3A4 | |
| SCHEMBL7314882 | 0.68 | NPC1 (0.41) | MAPTALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |