Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316945 | 0.88 | ALDH1A1 (0.36) | MAPTNPSR1HPGDALDH1A1POLB | |
| SCHEMBL7312638 | 0.86 | MAPT (0.35) | MAPTNPSR1HPGDALDH1A1POLB | |
| SCHEMBL7312257 | 0.83 | ALDH1A1 (0.37) | MAPTNPSR1HPGDALDH1A1POLB | |
| SCHEMBL7312248 | 0.79 | MAPT (0.39) | MAPTNPSR1HPGDALDH1A1RAB9A | |
| SCHEMBL7319259 | 0.73 | ATM (0.38) | MAPTNPSR1HPGDALDH1A1POLB | |
| SCHEMBL7309718 | 0.72 | ALDH1A1 (0.38) | MAPTALDH1A1RAB9ALMNATDP1 | |
| SCHEMBL7316959 | 0.72 | ALDH1A1 (0.35) | MAPTNPSR1HPGDALDH1A1POLB | |
| SCHEMBL7312650 | 0.70 | CA12 (0.35) | MAPTNPSR1HPGDALDH1A1POLB | |
| SCHEMBL7311157 | 0.69 | ATM (0.41) | MAPTHPGDALDH1A1POLBRAB9A | |
| SCHEMBL7316989 | 0.68 | MAPT (0.32) | MAPTNPSR1HPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |