Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.68 |
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206712 | 0.82 | SLC6A2 (0.62) | SLC6A2SLC6A3SLC6A4TACR1SMN1; SMN2 | |
| SCHEMBL14775500 | 0.81 | SLC6A2 (1.00) | SLC6A2SLC6A3SLC6A4TACR1HRH3 | |
| SCHEMBL14775419 | 0.80 | SLC6A2 (1.00) | SLC6A2SLC6A3SLC6A4HRH3 | |
| SCHEMBL14775283 | 0.79 | SLC6A2 (1.00) | SLC6A2SLC6A3SLC6A4TACR1HRH3 | |
| Hydrochloric Acid SCHEMBL8665660 | 0.78 | OPRM1 (0.48) | SLC6A2SLC6A3SLC6A4TACR1KCNQ2 | |
| SCHEMBL10399500 | 0.78 | SLC6A3 (0.58) | SLC6A2SLC6A3SLC6A4TACR1SMN1; SMN2 | |
| SCHEMBL29585404 | 0.78 | SLC6A3 (0.56) | SLC6A2SLC6A3SLC6A4SMN1; SMN2POLB | |
| SCHEMBL29585835 | 0.78 | SLC6A3 (0.56) | SLC6A2SLC6A3SLC6A4SMN1; SMN2POLB | |
| SCHEMBL22206766 | 0.78 | SLC6A3 (0.56) | SLC6A2SLC6A3SLC6A4SMN1; SMN2POLB | |
| SCHEMBL22206745 | 0.78 | SLC6A3 (0.56) | SLC6A2SLC6A3SLC6A4SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030335-A1 | A STEREOISOMERICALLY PURE NK-3 RECEPTOR ANTAGONIST AND CRYSTALLINE FORMS THEREOF | MILLENDO THERAPEUTICS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| EP-0673928-B1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI SYNTHELABO (FR) | 2001-08-29 | — | — | EP | disclosed |
| CN-1056605-C | Compounds as selective antagonists of human tachykinin III receptor and uses thereof | SANOFI CORP (FR) | 2000-09-20 | — | — | CN | disclosed |
| CN-1128756-A | Compounds as selective antagonists of the human tachykinin III receptor and uses thereof | SANOFI CORP (FR) | 1996-08-14 | — | — | CN | disclosed |
| EP-0673928-A1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI (FR) | 1995-09-27 | — | — | EP | disclosed |
| EP-0673928-A1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI (FR) | 1995-09-27 | — | — | EP | disclosed |