Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 16/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 16/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312913 | 0.81 | BLM (0.49) | — | |
| SCHEMBL313991 | 0.81 | BLM (0.49) | — | |
| SCHEMBL13714204 | 0.80 | AKR1C3 (0.51) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL4959239 | 0.78 | PKM (0.58) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL27648749 | 0.77 | AKR1C3 (0.44) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL10706064 | 0.77 | HTR2A (0.56) | — | |
| SCHEMBL1355576 | 0.77 | ACE2 (0.45) | AKR1C2AKR1C1 | |
| SCHEMBL12377744 | 0.77 | AKR1C3 (0.49) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL11141533 | 0.75 | FOLH1 (0.50) | — | |
| SCHEMBL264745 | 0.75 | FOLH1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227153-A1 | Site specific incorporation of keto amino acids into proteins | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-18 | — | — | US | disclosed |
| US-20080176284-A1 | Site specific incorporation of keto amino acids into proteins | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-07-24 | — | — | US | disclosed |
| US-20050266526-A1 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-12-01 | — | — | US | disclosed |
| US-20050209133-A1 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-09-22 | — | — | US | disclosed |
| US-20050186657-A1 | in vitro and in vivo; involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid; mimetics | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050266526-A1 | Glycoprotein synthesis | UGGT1, ST6GAL1, ANPEP | AKR1C3 4133/4885AKR1C2 3642/4885AKR1B10 3363/4885 |
| US-20050186657-A1 | in vitro and in vivo; involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid; mimetics | DNPEP, ANPEP, NPEPPS | AKR1C3 4651/4885AKR1C2 4303/4885AKR1B10 3938/4885 |
| US-20050209133-A1 | Glycoprotein synthesis | UGGT1, ST6GAL1, ANPEP | AKR1C3 4133/4885AKR1C2 3642/4885AKR1B10 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.