Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318581 | 0.88 | L3MBTL1 (0.41) | L3MBTL1PRCPALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7310181 | 0.86 | L3MBTL1 (0.39) | L3MBTL1PRCPALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7312977 | 0.80 | SIRT3 (0.43) | L3MBTL1ALDH1A1KDM4ESIRT3SMN1; SMN2 | |
| SCHEMBL7308548 | 0.77 | SIRT3 (0.39) | PRCPALDH1A1KDM4ESIRT3OPRM1 | |
| SCHEMBL7320392 | 0.73 | PRCP (0.36) | PRCPALDH1A1KDM4ESIRT3OPRM1 | |
| SCHEMBL7308468 | 0.69 | PDE3B (0.34) | PDE3A | |
| SCHEMBL7321178 | 0.69 | PDE3B (0.36) | CYP2D6LMNACYP1A2PDE3A | |
| SCHEMBL7318574 | 0.67 | MEN1 (0.41) | L3MBTL1ALDH1A1KDM4ESIRT3SMN1; SMN2 | |
| SCHEMBL3235313 | 0.67 | PRCP (0.51) | PRCPALDH1A1SMN1; SMN2OPRM1MEN1 | |
| SCHEMBL7317245 | 0.65 | PDE3B (0.44) | L3MBTL1ALDH1A1KDM4ECYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |