Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312987 | 0.88 | L3MBTL1 (0.41) | L3MBTL1OPRM1ALDH1A1PRCPKDM4E | |
| SCHEMBL7310181 | 0.87 | L3MBTL1 (0.39) | L3MBTL1OPRM1ALDH1A1PRCPKDM4E | |
| SCHEMBL7318574 | 0.79 | MEN1 (0.41) | L3MBTL1OPRM1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7320392 | 0.77 | PRCP (0.36) | OPRM1ALDH1A1PRCPKDM4EOPRK1 | |
| SCHEMBL7308548 | 0.73 | SIRT3 (0.39) | OPRM1ALDH1A1PRCPKDM4EOPRK1 | |
| SCHEMBL7308468 | 0.70 | PDE3B (0.34) | — | |
| SCHEMBL7321178 | 0.69 | PDE3B (0.36) | CYP2D6 | |
| SCHEMBL7312977 | 0.68 | SIRT3 (0.43) | L3MBTL1OPRM1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7310172 | 0.66 | DRD2 (0.41) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2CYP2D6 | |
| SCHEMBL3235313 | 0.65 | PRCP (0.51) | OPRM1ALDH1A1PRCPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |