Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320392 | 0.88 | PRCP (0.36) | SIRT3PRCPALDH1A1MAPTOPRM1 | |
| SCHEMBL7311807 | 0.86 | PRCP (0.34) | PRCPALDH1A1MAPTOPRM1OPRK1 | |
| SCHEMBL7308539 | 0.79 | SIRT3 (0.52) | SIRT3PRCPALDH1A1MAPTOPRM1 | |
| SCHEMBL7316010 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPTOPRK1MEN1KMT2A | |
| SCHEMBL7309718 | 0.74 | ALDH1A1 (0.38) | SIRT3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7318581 | 0.73 | L3MBTL1 (0.41) | PRCPALDH1A1OPRM1OPRK1KDM4E | |
| SCHEMBL7311157 | 0.73 | ATM (0.41) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7310181 | 0.71 | L3MBTL1 (0.39) | PRCPALDH1A1MAPTOPRM1KDM4E | |
| SCHEMBL10375774 | 0.71 | PDE3B (0.59) | — | |
| SCHEMBL7318298 | 0.71 | KDM4E (0.45) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |