SCHEMBL731336

SCHEMBL731336

O=C1C=C(c2ccccc2)CC1

nearest known ligand 0.75

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.50
RAB9A P51151 1/20 0.50
ALDH1A1 P00352 3/20 0.44
LMNA P02545 2/20 0.44
CFTR P13569 2/20 0.41
GOPC Q9HD26 2/20 0.41
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
BACE1 P56817 1/20 0.39
HPGD P15428 1/20 0.39
PDE4B Q07343 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL679561 0.86 NPC1 (0.47) NPC1RAB9AALDH1A1LMNACFTR
SCHEMBL7959486 0.82 NPC1 (0.52) NPC1RAB9AALDH1A1LMNACFTR
SCHEMBL16321456 0.78 CYP11B2 (0.58) ALDH1A1LMNAMAPTHTTHPGD
SCHEMBL7975852 0.78 PARP10 (0.42)
SCHEMBL728745 0.78 GSTP1 (0.50) NPC1RAB9AALDH1A1
SCHEMBL9059926 0.77 NCOA1 (0.45) NPC1RAB9AALDH1A1BACE1MAOA
SCHEMBL24924592 0.76 CYP11B1 (0.45) NPC1RAB9ALMNAMAPTHTT
SCHEMBL5228519 0.76 HTR2C (0.39) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL27720413 0.75 MT-CO2 (0.42) NPC1RAB9AALDH1A1LMNAMAPT
SCHEMBL14102137 0.73 CLK4 (0.45) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4173550-A ORGANOLEPTIC FIRMENICH SA (CH) 1979-11-06 US claimed
US-4144200-A 3-Phenyl-cyclopent-2-en-1-one in perfume compositions FIRMENICH SA (CH) 1979-03-13 US claimed
US-12509418-B2 Chromophoric compounds and UV-absorbing compositions LYGG CORPORATION (US) 2025-12-30 US disclosed
US-20250270164-A1 CHROMOPHORIC COMPOUNDS AND UV-ABSORBING COMPOSITIONS LYGG CORPORATION 2025-08-28 US disclosed
EP-2438989-B1 USE OF ASYMMETRIC HYDROGENATION CATALYST TAKASAGO PERFUMERY CO LTD (JP) 2016-04-13 EP disclosed
US-9000192-B2 Catalyst for asymmetric hydrogenation and method for manufacturing optically active carbonyl compound using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-04-07 US disclosed
US-9000192-B2 Catalyst for asymmetric hydrogenation and method for manufacturing optically active carbonyl compound using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-04-07 US disclosed
US-8785494-B2 Calcium sensing receptor modulating compounds and pharmaceutical use thereof LEO-PHARMA A/S (DK) 2014-07-22 US disclosed
US-8674144-B2 Catalyst for asymmetric hydrogenation and method for manufacturing optically active carbonyl compound using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-03-18 US disclosed
US-8674144-B2 Catalyst for asymmetric hydrogenation and method for manufacturing optically active carbonyl compound using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-03-18 US disclosed
US-20130217895-A1 CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-08-22 US disclosed
EP-0559743-B1 NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE PFIZER (US) 1995-03-08 EP disclosed
US-5279999-A Catalyst composition SHELL OIL COMPANY (US) 1994-01-18 US disclosed
EP-0559743-A1 NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE. PFIZER HOSPITAL PROD (US) 1993-09-15 EP disclosed
EP-0540108-A1 Catalyst composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-05-05 EP disclosed
WO-1992009566-A1 NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE PFIZER INC. (US) 1992-06-11 WO disclosed
US-4173550-A ORGANOLEPTIC FIRMENICH SA (CH) 1979-11-06 US disclosed
US-4173550-A ORGANOLEPTIC FIRMENICH SA (CH) 1979-11-06 US disclosed
US-4144200-A 3-Phenyl-cyclopent-2-en-1-one in perfume compositions FIRMENICH SA (CH) 1979-03-13 US disclosed
US-4144200-A 3-Phenyl-cyclopent-2-en-1-one in perfume compositions FIRMENICH SA (CH) 1979-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270164-A1 CHROMOPHORIC COMPOUNDS AND UV-ABSORBING COMPOSITIONS ERCC1, TYR, ERCC5 NPC1 1517/4885RAB9A 2211/4885ALDH1A1 1196/4885
US-12509418-B2 Chromophoric compounds and UV-absorbing compositions LBR, ERCC1, MC1R NPC1 968/4885RAB9A 2940/4885ALDH1A1 1591/4885
US-20130217895-A1 CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME HMOX1, NQO1, CBR3 NPC1 1457/4885RAB9A 3893/4885ALDH1A1 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.