Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303559 | 0.87 | GAA (0.44) | GAATSHRANPEP | |
| SCHEMBL1168970 | 0.84 | POLB (0.49) | POLBCTDSP1APAF1 | |
| SCHEMBL17161710 | 0.80 | MEN1 (0.53) | MAPTPOLBCTDSP1APAF1 | |
| SCHEMBL7317844 | 0.80 | GAA (0.43) | GAATSHRANPEP | |
| SCHEMBL1643461 | 0.80 | MEN1 (0.48) | MAPTPOLBCTDSP1APAF1 | |
| SCHEMBL310099 | 0.80 | MEN1 (0.48) | MAPTPOLBCTDSP1APAF1 | |
| SCHEMBL1643467 | 0.80 | MEN1 (0.48) | MAPTPOLBCTDSP1APAF1 | |
| Hydrochloric Acid SCHEMBL310111 | 0.79 | MEN1 (0.47) | MAPTPOLBCTDSP1APAF1 | |
| Hydrochloric Acid SCHEMBL310112 | 0.79 | MEN1 (0.47) | MAPTPOLBCTDSP1APAF1 | |
| SCHEMBL7305459 | 0.79 | MTNR1A (0.48) | GAATSHRANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |