SCHEMBL7303559

SCHEMBL7303559

CSCC[C@H](NC(c1ccccc1)c1ccccc1)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.43
ANPEP P15144 1/20 0.43
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CRHBP P24387 1/20 0.41
KMT2A Q03164 1/20 0.41
CRHR2 Q13324 1/20 0.41
LMNA P02545 2/20 0.41
PKM P14618 1/20 0.41
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
CA2 P00918 2/20 0.40
CA1 P00915 1/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7313416 0.87 MAPT (0.44) GAATSHRANPEP
SCHEMBL7317844 0.81 GAA (0.43) GAATSHRANPEPMEN1ALDH1A1
SCHEMBL7305459 0.80 MTNR1A (0.48) GAATSHRANPEPMEN1ALDH1A1
SCHEMBL7317031 0.77 MMP9 (0.46) ALDH1A1LMNA
SCHEMBL7307221 0.77 LMNA (0.41) GAATSHRALDH1A1KMT2ALMNA
SCHEMBL7265651 0.77 ANPEP (0.55) GAATSHRANPEP
SCHEMBL4388416 0.77 MEN1 (0.63) TSHRMEN1ALDH1A1CRHBPKMT2A
SCHEMBL4388419 0.77 MEN1 (0.63) TSHRMEN1ALDH1A1CRHBPKMT2A
SCHEMBL11224097 0.77 GAA (0.50) GAAALDH1A1LMNAPKMFNTA
SCHEMBL7317017 0.76 CTSK (0.47) TSHRMEN1ALDH1A1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041064-A2 N-substituted alpha aminoacid amides as calcium channel modulators ELI LILLY AND COMPANY LIMITED (GB) 2000-10-04 EP disclosed
EP-0805147-A1 Novel N-substituted alpha aminoacid amides as calcium channel modulators LILLY INDUSTRIES LIMITED (GB) 1997-11-05 EP disclosed