Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317844 | 0.90 | GAA (0.43) | MTNR1AMTNR1BLMNAMEN1ALDH1A1 | |
| SCHEMBL7313618 | 0.83 | CA1 (0.47) | FNTAFNTBGAAOPRK1ANPEP | |
| SCHEMBL10764115 | 0.81 | GGT1 (0.52) | CYP2D6CYP2C19KMT2AFNTAFNTB | |
| Hydrochloric Acid SCHEMBL11094927 | 0.80 | GGT1 (0.51) | CYP2D6CYP2C19MEN1KMT2AFNTA | |
| SCHEMBL7303559 | 0.80 | GAA (0.44) | LMNAMEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL7319574 | 0.80 | CASR (0.53) | MTNR1AMTNR1BCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7265651 | 0.80 | ANPEP (0.55) | TSHRGAAANPEP | |
| SCHEMBL7313416 | 0.79 | MAPT (0.44) | TSHRGAAANPEP | |
| SCHEMBL7317918 | 0.78 | CTSK (0.46) | MTNR1AMTNR1BLMNAMEN1ALDH1A1 | |
| SCHEMBL9190837 | 0.77 | TSHR (0.38) | LMNAALDH1A1TSHRFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |