Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305459 | 0.90 | MTNR1A (0.48) | GAATSHRANPEPFNTAFNTB | |
| SCHEMBL7265651 | 0.81 | ANPEP (0.55) | GAATSHRANPEP | |
| SCHEMBL7303559 | 0.81 | GAA (0.44) | GAATSHRANPEPCA12CA9 | |
| SCHEMBL7313416 | 0.80 | MAPT (0.44) | GAATSHRANPEP | |
| SCHEMBL7310003 | 0.79 | MMP1 (0.39) | ANPEPCA12CA9FNTAFNTB | |
| SCHEMBL7313618 | 0.79 | CA1 (0.47) | GAAANPEPFNTAFNTB | |
| SCHEMBL8083546 | 0.78 | ERAP2 (0.45) | MTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL10764115 | 0.77 | GGT1 (0.52) | ANPEPFNTAFNTBPGGT1BKMT2A | |
| SCHEMBL7305458 | 0.76 | CTSK (0.46) | TSHRFNTAFNTBPGGT1BMEN1 | |
| Hydrochloric Acid SCHEMBL11094927 | 0.76 | GGT1 (0.51) | ANPEPFNTAFNTBPGGT1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |