Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351296 | 0.91 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7317727 | 0.91 | ALDH1A1 (0.37) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL7320732 | 0.89 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7311541 | 0.84 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DPRMT5 | |
| SCHEMBL7311518 | 0.75 | ALDH1A1 (0.37) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL7319183 | 0.75 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7311440 | 0.72 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7313463 | 0.70 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL7307752 | 0.69 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7309595 | 0.69 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |