Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313455 | 0.89 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7317727 | 0.86 | ALDH1A1 (0.37) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7351296 | 0.86 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7311440 | 0.83 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7311541 | 0.72 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7311518 | 0.70 | ALDH1A1 (0.37) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7319183 | 0.70 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7317857 | 0.69 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7320121 | 0.69 | PDE3B (0.37) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7320735 | 0.68 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761416-A | ENZYME INHIBITORS, INOTROPIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-02 | — | — | US | disclosed |
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |