Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319259 | 0.88 | ATM (0.38) | ATMNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL7317428 | 0.88 | ATM (0.38) | ATMNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL7316814 | 0.80 | NPC1 (0.42) | ATMNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL7311157 | 0.76 | ATM (0.41) | ATMNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL7311396 | 0.75 | ATM (0.41) | ATMNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL7314872 | 0.74 | NPC1 (0.40) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL7314546 | 0.72 | PDE3B (0.39) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7315285 | 0.71 | PDE3B (0.41) | MEN1KMT2ATSHRMAPTTDP1 | |
| SCHEMBL7316945 | 0.71 | ALDH1A1 (0.36) | ATMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7309718 | 0.71 | ALDH1A1 (0.38) | ATMNPC1RAB9AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |