Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292069 | 0.80 | CYP2C9 (0.78) | CYP2C9MEN1CYP3A4KMT2APMP22 | |
| SCHEMBL7302781 | 0.73 | HTR4 (0.45) | CYP2C9MEN1CYP3A4KMT2APMP22 | |
| SCHEMBL7291933 | 0.72 | HTR4 (0.61) | CYP2C9MEN1CYP3A4KMT2APMP22 | |
| SCHEMBL2940596 | 0.71 | CYP2C9 (0.94) | CYP2C9MEN1CYP3A4KMT2APMP22 | |
| SCHEMBL29385613 | 0.71 | CYP2C9 (0.94) | CYP2C9MEN1CYP3A4KMT2APMP22 | |
| SCHEMBL7302574 | 0.71 | CYP2C9 (0.95) | CYP2C9MEN1CYP3A4KMT2APMP22 | |
| Hydrochloric Acid SCHEMBL7295175 | 0.71 | CYP2C9 (0.92) | CYP2C9MEN1CYP3A4KMT2APMP22 | |
| SCHEMBL7305753 | 0.70 | CNR1 (0.52) | CYP2C9MEN1CYP3A4KMT2APMP22 | |
| SCHEMBL7310046 | 0.70 | ACHE (0.46) | CYP2C9MEN1CYP3A4KMT2APMP22 | |
| Maleic Acid SCHEMBL7302318 | 0.69 | CYP2C9 (0.86) | CYP2C9MEN1CYP3A4KMT2APMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501322-B1 | 3-Piperidinylmethylcarboxylate substituted indoles | GLAXO GROUP LTD (GB) | 1996-09-04 | — | — | EP | claimed |