Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324009 | 0.83 | SIGMAR1 (0.44) | KMT2AF2MEN1L3MBTL1ALDH1A1 | |
| SCHEMBL7323738 | 0.83 | CYP1A2 (0.40) | KMT2AF2MEN1GAAL3MBTL1 | |
| SCHEMBL7309756 | 0.81 | SLC18A3 (0.42) | IDO1KMT2ASLC18A3MEN1HSP90AA1 | |
| SCHEMBL7321503 | 0.81 | SLC18A3 (0.42) | IDO1KMT2ASLC18A3MEN1HSP90AA1 | |
| SCHEMBL7325916 | 0.80 | F2 (0.44) | KMT2AF2MEN1GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7321516 | 0.80 | SLC18A3 (0.41) | IDO1KMT2ASLC18A3MEN1HSP90AA1 | |
| SCHEMBL7324554 | 0.73 | TSHR (0.40) | KMT2AF2MEN1GAAL3MBTL1 | |
| SCHEMBL7320685 | 0.71 | SIGMAR1 (0.42) | — | |
| SCHEMBL27953270 | 0.69 | HSP90AA1 (0.44) | KMT2ASLC18A3HSP90AA1ALDH1A1HTT | |
| SCHEMBL1355340 | 0.68 | HSD11B1 (0.49) | KMT2ACASP6MEN1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |