Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324009 | 0.84 | SIGMAR1 (0.44) | F2L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL7323738 | 0.84 | CYP1A2 (0.40) | F2L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL7324554 | 0.82 | TSHR (0.40) | F2L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL7313735 | 0.80 | IDO1 (0.41) | F2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL10692330 | 0.74 | MAPT (0.46) | ALDH1A1CYP1A2CYP3A4CYP2C19HAO1 | |
| SCHEMBL7317851 | 0.74 | HDAC8 (0.46) | L3MBTL1KMT2AHAO1 | |
| SCHEMBL7314337 | 0.74 | FFAR1 (0.54) | L3MBTL1KMT2AHAO1 | |
| Hydrochloric Acid SCHEMBL7317863 | 0.72 | FFAR1 (0.53) | L3MBTL1KMT2AHAO1 | |
| SCHEMBL1831403 | 0.72 | SLC6A2 (0.56) | HAO1SLC6A2SLC6A4 | |
| SCHEMBL7320685 | 0.69 | SIGMAR1 (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154483-C | Use of amines to produce drugs for preventing tumour cell proliferation | ��ŵ��-ʥ�������ɷ�����˾ | 2004-06-23 | — | — | CN | disclosed |
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |
| CN-1226825-A | Use of amines to produce drugs for preventing tumour cell proliferation | SANOFI SA (FR) | 1999-08-25 | — | — | CN | disclosed |
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |