Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324009 | 0.85 | SIGMAR1 (0.44) | TSHRF2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7325916 | 0.82 | F2 (0.44) | TSHRF2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL7319301 | 0.78 | HPGD (0.34) | NPC1RAB9A | |
| SCHEMBL7313183 | 0.77 | FFAR1 (0.41) | — | |
| SCHEMBL7323738 | 0.76 | CYP1A2 (0.40) | TSHRF2L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7319313 | 0.76 | FFAR1 (0.40) | — | |
| SCHEMBL7313735 | 0.73 | IDO1 (0.41) | TSHRF2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL7320685 | 0.72 | SIGMAR1 (0.42) | LMNA | |
| SCHEMBL7321171 | 0.68 | GPR88 (0.44) | — | |
| SCHEMBL7319274 | 0.66 | CNR2 (0.42) | MEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |