Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310444 | 0.84 | LTA4H (0.42) | ALDH1A1 | |
| SCHEMBL7323329 | 0.79 | BIRC2 (0.53) | MAPK1NPC1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7320285 | 0.79 | LTA4H (0.52) | TSHRKMT2A | |
| SCHEMBL7321257 | 0.78 | LTA4H (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7313736 | 0.78 | LTA4H (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7319825 | 0.76 | MAPT (0.58) | MAPK1SMN1; SMN2L3MBTL1TSHRALDH1A1 | |
| SCHEMBL7320822 | 0.73 | LTA4H (0.47) | L3MBTL1 | |
| SCHEMBL7309902 | 0.72 | LTA4H (0.48) | HPGD | |
| SCHEMBL7314012 | 0.72 | ALDH1A1 (0.51) | MAPK1NPC1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL7314034 | 0.72 | ALDH1A1 (0.51) | MAPK1NPC1SMN1; SMN2L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |