Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 18/20 | 0.65 |
| ▸ | MAOA | P21397 | 17/20 | 0.65 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310807 | 0.90 | MAOB (0.69) | MAOBMAOADRD2HTR6 | |
| SCHEMBL7309846 | 0.82 | MAOA (0.69) | MAOBMAOADRD2HTR6 | |
| SCHEMBL31414465 | 0.80 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL6721655 | 0.80 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL7311963 | 0.79 | MAOA (0.53) | MAOBMAOADRD2 | |
| SCHEMBL7306995 | 0.75 | MAOB (0.64) | MAOBMAOADRD2 | |
| SCHEMBL7306333 | 0.73 | ALDH1A1 (0.49) | MAOB | |
| SCHEMBL15413967 | 0.73 | MAOB (0.85) | MAOBMAOA | |
| SCHEMBL7318395 | 0.73 | KDM4C (0.44) | — | |
| SCHEMBL16048700 | 0.73 | MAOB (1.00) | MAOBMAOADRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |