Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314006 | 1.00 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL7314012 | 1.00 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL7314023 | 0.87 | MEN1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL7317378 | 0.85 | CA2 (0.45) | — | |
| SCHEMBL7317352 | 0.85 | CA2 (0.45) | — | |
| SCHEMBL7317343 | 0.85 | CA2 (0.45) | — | |
| SCHEMBL7307744 | 0.82 | MME (0.49) | — | |
| SCHEMBL7322360 | 0.82 | MME (0.49) | — | |
| SCHEMBL7307711 | 0.82 | MME (0.49) | — | |
| SCHEMBL7307690 | 0.82 | MME (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |