Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | REN | P00797 | 10/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | CTSE | P14091 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314034 | 0.87 | ALDH1A1 (0.51) | MEN1ALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL7314006 | 0.87 | ALDH1A1 (0.51) | MEN1ALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL7314012 | 0.87 | ALDH1A1 (0.51) | MEN1ALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL7317366 | 0.85 | CA2 (0.56) | RENAGTR2MMEECE1 | |
| SCHEMBL7322345 | 0.81 | MME (0.59) | RENAGTR2MMEECE1 | |
| SCHEMBL7307725 | 0.81 | MME (0.59) | RENAGTR2MMEECE1 | |
| SCHEMBL7347178 | 0.80 | AGTR2 (0.55) | RENAGTR2MMEECE1 | |
| SCHEMBL7314274 | 0.80 | MRGPRX4 (0.56) | RENAGTR2MMEECE1 | |
| SCHEMBL7314528 | 0.80 | MRGPRX4 (0.56) | RENAGTR2MMEECE1 | |
| SCHEMBL7323329 | 0.79 | BIRC2 (0.53) | MEN1ALDH1A1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |